The West African Ebola Virus Disease (EVD) outbreak in 2014/15 posed a number of urban-specific challenges to humanitarians responding to the crisis. One of these related to controlling the rapid spread of the disease across the urban landscape. Guinea, Liberia and Sierra Leone used quarantine at various points, which was by and large ill received, particularly in urban centres. This paper focuses specifically on the use of quarantine in urban environments during the humanitarian response to the Ebola Crisis.